What Causes Digital Dermatitis?

Digital dermatitis is primarily caused by bacteria from the Treponema genus, a group of spirochaetes. These long, thin organisms with hair-like filaments penetrate the outer skin of the hoof, burrow into the deeper skin layers, and multiply within the tissue.

Early-stage infections cause acute, intense pain because the bacteria are actively invading living tissue. As the infection becomes chronic, the lesion changes character but remains a reservoir of bacteria that can reinfect the same animal or spread to others.

The disease was first described in the early 1970s by Italian veterinarian Dr. Mortellaro. It has been in dairy barns ever since.

Digital dermatitis is a painful infectious hoof disease primarily caused by Treponema bacteria

How Are DD Lesions Classified?

The M-stage classification, developed by Dr. Dopfer (University of Wisconsin-Madison School of Veterinary Medicine), is the standard framework for describing digital dermatitis. The "M" stands for Mortellaro. Five stages describe the full progression of the disease.

M0: Healthy Photo: healthy hoof skin, no lesion
Stage 1 of 5

No Lesion

Normal digital skin. Most common in calves and pre-partum heifers. Increasingly rare in adult dairy cows.

Healthy tissue Baseline

How Does Digital Dermatitis Spread Between Cows?

Spread happens through contact with DD bacteria in manure and contaminated environments. Any surface that carries infected material from one hoof to another is a risk.

Footbaths are a particular concern. A poorly managed footbath stops being a prevention tool and becomes a transmission vector. If the solution is not refreshed and the bath is heavily contaminated, cows walk through it and pick up bacteria rather than killing them.

Feedlots have also seen increasing DD cases. These farms often purchase cows from auction sales, and cattle are transported on liners where close contact makes spreading easy. Purchased cattle are a real route of entry for DD into a clean herd.

DD bacteria have also been found in elk and sheep, though the primary concern in dairy hoof care is cattle.

Differential Diagnosis

DD lesions at the heel are distinct from foot rot, which causes swelling between the toes and a foul smell. DD can also develop on top of an open interdigital corn lesion. If finding DD in several cows, also look for interdigital dermatitis. Both conditions are often found in the same herd.

Not sure which condition you are looking at?

Download the free Hoof Disease Reference Chart: DD, foot rot, interdigital dermatitis, and corn side by side.

Download Free Chart

Where on the Hoof Is DD Found?

The most common location is the skin at the back of the heel, between the heel bulbs. It also occurs in the interdigital space between the two claws, and along the coronary band at the front of the hoof. Treponema bacteria have also been found in association with sole ulcers and toe necrosis, though the heel bulb region is where the disease classically starts.

Digital dermatitis location on a cow's hoof — heel bulbs, interdigital space, and coronary band

How to Treat Digital Dermatitis

This disease is relatively easy to treat when caught early. For years, tetracycline-based products such as Tetra 1000 mixed with iodine cream were the standard treatment. Since 2006, Diamond Hoof Care has treated digital dermatitis without antibiotics using Intra Hoof-fit Gel.

Antibiotic-free since 2006.

Diamond Hoof Care has treated digital dermatitis without antibiotics for nearly two decades, long before antimicrobial stewardship became a regulatory priority in Canadian dairy.

1.58x
More effective than conventional antibiotic treatments
Holzhauer et al., 2011, Veterinary Record
92%
Cure rate at Day 28 for M2 lesions
Dutch trial: 94 hindfeet, 5 herds
100%
Transition from M2 by Day 7
Canadian registration trial: 50 lesions, 3 farms

The Treatment Protocol

Trim the cow regularly to keep her hooves in optimal condition.
Dry the skin first. Use a paper towel or dry cloth between and at the back of the hoof. Do not use water on the lesion before applying the gel.
Brush the Intra Hoof-fit Gel between and on the back of the hoof, directly onto the lesion.
Apply a wrap on severe cases and leave it on for 3 to 4 days.
Some cows need a second brushing with the gel without a wrap. Check at Day 3.

For a detailed walkthrough including what to watch for at Day 3, see how to best treat strawberry foot in cattle.

Video: Non-Antibiotic Treatment Explained

Dr. Menno Holzhauer from the Dutch Animal Health Service and Pieter Kloosterman, trainer at the Hoof Trimming Training Center, explain the use of non-antibiotic products.

Health Canada Registered: DIN 02441284 Safety and efficacy demonstrated. Why DIN registration matters

Intra Hoof-fit Gel

Intra Hoof-fit Gel — DIN-registered non-antibiotic topical treatment for digital dermatitis in dairy cattle
DIN Registered

Intra Hoof-fit Gel

The first and only non-antibiotic topical medication for digital dermatitis treatment registered with a DIN in Canada. Developed by Intracare BV (Netherlands) and exclusively distributed in Canada by Diamond Hoof Care Ltd. since 2006.

View Product

Frequently Asked Questions About Digital Dermatitis

DD is classified using five M-stages developed by Dr. Dopfer. M0 is healthy skin with no lesion. M1 is a small, early red or gray defect under 2 cm. M2 is the active, painful ulcerative stage, over 2 cm and highly contagious. M3 is the healing stage after treatment, where a firm scab forms. M4 is the chronic stage: thickened or proliferative tissue that can reactivate into M2.

Dry the hoof skin with a cloth, never water. Brush Intra Hoof-fit Gel directly onto the lesion. Wrap severe cases and leave the wrap for 3 to 4 days. Check at Day 3: most cows will have healed. Re-apply the gel without a wrap to any remaining cases. A small number may need one more wrap application at Day 7. This antibiotic-free protocol has been in use since 2006.

For a full step-by-step guide, see how to best treat strawberry foot in cattle.

Yes. DD spreads through contact with infected manure and contaminated surfaces. A footbath that is not refreshed regularly can become an infection source instead of a prevention tool. Purchased cattle and cattle transported on liners from auction sales are a common entry point for DD into a herd. Research shows M4 lesions account for over 88% of digital dermatitis transmission in a herd. Not because M4 is more acutely infectious, but because chronic lesions persist for months and go untreated (Worby et al., 2017).

An active M2 lesion looks like a raw strawberry: red, moist, painful, and often surrounded by a fringe of long hairs. This is why the disease is also called hairy warts. Chronic M4 lesions are grayish and proliferative, with a roughened wart-like surface. Early M1 lesions are small, under 2 cm, and easy to miss without regular inspection.

With timely treatment, most M2 lesions transition to the M3 healing stage within one to two days of the first Intra Hoof-fit Gel application and wrap. A typical acute case is effectively treated within 7 days. Chronic M4 lesions take longer, are harder to resolve fully, and can reactivate into M2 if the herd reservoir is not managed. Healing time depends on stage caught, application accuracy, and whether the underlying conditions have been corrected.

How to Prevent Digital Dermatitis

A clean, dry environment with good ventilation is the foundation. Managing DD prevention means managing the conditions that let Treponema bacteria survive and spread.

If possible, reduce the risk of buying the disease into a herd. Ask where cattle come from and whether the herd of origin has active DD.

Both Intra Hoof Sol Spray and Hoof Sol Bath are registered with Health Canada as Veterinary Health Products (VHP). Weekly hoof spraying sessions with Intra Hoof Sol Spray are effective as part of a prevention protocol. For farms running a footbath, Hoof Sol Bath is the registered option.

Copper sulphate and formalin were common footbath ingredients for years. Farmer safety, environmental impact, and questions about efficacy are reasons to choose registered alternatives.

Free Download: Hoof Disease Reference Chart

Diamond Hoof Care has supported Canadian dairy farms with antibiotic-free hoof care since 2006. This side-by-side chart compares digital dermatitis, foot rot, interdigital dermatitis, and other common cattle hoof diseases, so you can sort one from another at the chute before you reach for a treatment.

Download Free Chart
Hoof Disease Reference Chart preview